Multiscale Operational Organic Chemistry

This comprehensive laboratory text provides a thorough introduction to all of the significant operations used in the organic lab and includes a large selection of traditional-scale and microscale experiments ... Les mer

Multiscale Operational Organic Chemistry

This comprehensive laboratory text provides a thorough introduction to all of the significant operations used in the organic lab and includes a large selection of traditional-scale and microscale experiments and minilabs. Its unique problem-solving approach encourages students to think in the laboratory by solving a scientific problem in the process of carrying out each experiment. The Second Edition contains a new introductory section, "Chemistry and the Environment," which includes a discussion of the principles of green chemistry. Several green experiments have been added, and some experiments from the previous editions have been revised to make them greener.

Preface To the Instructor Acknowledgments Introduction Problem Solving in the Organic Chemistry Laboratory Scientific Methodology Organization of This Book A Guide to Success in the Organic Chemistry Lab Laboratory Safety Safety Standards Protecting Yourself Preventing Laboratory Accidents Reacting to Accidents: First Aid Reacting to Accidents: Fire Chemical Hazards Finding and Using Chemical Safety Information Chemistry and the Environment Disposal of Hazardous Wastes Green Chemistry Part I Mastering the Operations 1. Learning Basic Operations. The Effect of pH on a Food Preservative 2. Extraction and Evaporation. Separating the Components of "Panacetin" 3. Recrystallization and Melting-Point Measurement. Identifying a Constituent of "Panacetin" 4. Heating Under Reflux. Synthesis of Salicylic Acid from Wintergreen Oil 5. Simple Distillation, Gas Chromatography. Preparation of Synthetic Banana Oil 6. Fractional Distillation. Separation of Petroleum Hydrocarbons 7. Addition, Sublimation. A Green Synthesis of Camphor 8. Boiling Point, Refractive Index. Identification of a Petroleum Hydrocarbon 9. Column Chromatography, UV-VIS Spectrometry. Isolation and Isomerization of Lycopene from Tomato Paste 10. Steam Distillation, Infrared Spectrometry. Isolation and Identification of the Major Constituent of Clove Oil 11. Thin-Layer Chromatography, NMR Spectrometry. Identification of Unknown Ketones 12. Vacuum Distillation, Optical Rotation. The Optical Activity of a-Pinene: A Chemical Mystery Part II Correlated Laboratory Experiments 13. Investigation of a Chemical Bond by Infrared Spectrometry 14. Properties of Common Functional Groups 15. Thin-Layer Chromatographic Analysis of Drug Components 16. Separation of an Alkane Clathrate 17. Isomers and Isomerization Reactions 18. Structures and Properties of Stereoisomers 19. Bridgehead Reactivity in an SN1Solvolysis Reaction 20. Reaction of Iodoethane with Sodium Saccharin, an Ambident Nucleophile 21. Dehydration of Methylcyclohexanols and the Evelyn Effect 22. Testing Markovnikov's Rule 23. Stereochemistry of Bromine Addition to trans-Cinnamic Acid 24. A Green Synthesis of Adipic Acid 25. Preparation of Bromotriphenylmethane and the Trityl Free Radical 26. Chain-Growth Polymerization of Styrene and Methyl Methacrylate 27. Synthesis of Ethanol by Fermentation 28. Reaction of Butanols with Hydrobromic Acid 29. Borohydride Reduction of Vanillin to Vanillyl Alcohol 30. Synthesis of Triphenylmethanol and the TritylCarbocation 31. An Unexpected Reaction of 2,3-Dimethyl-2,3-butanediol 32. Identification of a Conjugated Diene from Eucalyptus Oil 33. Spectral Identification of Monoterpenes 34. Synthesis and Spectral Analysis of Aspirin 35. Directive Effects in the Bromination of Vanillin 36. Mechanism of the Nitration of Arenes by Nitronium Fluoborate 37. Friedel-Crafts Acylation of Anisole 38. Determination of the Structure of a Natural Product in Anise Oil 39. Identification of an Oxygen-Containing Organic Compound 40. Oxidation of the Insect Repellent "6-12" 41. Isomerization of a Cyclic Ketone 42. A Wittig Reaction of trans-Cinnamaldehyde 43. Effect of Reaction Conditions on the Condensation of Furfural with Cyclopentanone 44. Electronic Effect of a para-I

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