This issue of Anesthesiology Clinics, guest edited by Drs. Jeffrey Kirsch and Cindy Lien, focuses on Neuroanesthesia. This is one of four issues each year selected by the series consulting editor, Dr. Lee Fleisher. Articles in this issue include, but are not limited to: Degenerative Spine Disease, Craniosynostosis, Supratentorial tumors (including awake craniotomies), Suboccipital Procedures, Acute Stroke, Acute Spinal cord injury, Decompressive surgery for patients with TBI, Neuromonitoring and more.