Imaging Technologies and Transdermal Delivery in Skin Disorders

Chenjie Xu (Redaktør) ; Xiaomeng Wang (Redaktør) ; Manojit Pramanik (Redaktør)

Provides the latest information on imaging technologies and transdermal delivery in skin disorders



This important, timely book covers the latest understanding about today's major skin disorders, the development of imaging technologies for skin diagnosis, and the applications of micro/nano-technologies for the treatment of skin complications. Les mer
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Vår pris: 2110,-

(Innbundet) Fri frakt!
Leveringstid: Sendes innen 21 dager
På grunn av Brexit-tilpasninger og tiltak for å begrense covid-19 kan det dessverre oppstå forsinket levering.

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Provides the latest information on imaging technologies and transdermal delivery in skin disorders



This important, timely book covers the latest understanding about today's major skin disorders, the development of imaging technologies for skin diagnosis, and the applications of micro/nano-technologies for the treatment of skin complications. It also places great emphasis on the critical role that interdisciplinary science occupies to achieve the requisite level of understanding of skin conditions and their management, which is essential to creating technologies that work.



Imaging Technologies and Transdermal Delivery in Skin Disorders starts by outlining the structural characteristics of skin and skin appendages. It then discusses the key pathways involved in skin growth and development. Clinical presentations, pathophysiological mechanisms, and current clinical practices used to treat diseases affecting the skin are then introduced. Common preclinical models used for studying the mechanisms of diverse skin diseases, validation of novel therapeutic targets, and screening of new drugs to treat these diseases are also covered. The book examines the latest imaging technologies for understanding in vivo skin changes, as well as technologies such as high-resolution ultrasound imaging, quantitative Magnetic Resonance Imaging, high-resolution Optical Coherence Tomography, and emerging hybrid-imaging modalities. It concludes with chapters introducing emerging drug delivery technologies and potential future innovative developments.



* Presents up-to-date knowledge of the skin biology and pathologies

* Introduces advancements in the topic of imaging technology for tracing the drug delivery process, which is rarely systematically reported by other counterparts

* Covers the latest development in three inter-related directions of drug delivery, imaging, and skin disease intersect for skin research

* Provides an overview of the latest development of diagnostic and therapeutic technologies for skin diseases

Imaging Technologies and Transdermal Delivery in Skin Disorders will be of great interest to analytical chemists, materials scientists, pharmaceutical chemists, clinical chemists, biotechnologists, bioengineers, cosmetics industry, and dermatologists.

Fakta

Innholdsfortegnelse

Foreword xvii


1 Skin Structure and Biology 1
Wei-Meng Woo


1.1 Introduction 1


1.2 Skin Structure 2


1.2.1 Overview of Skin Tissue Organization 2


1.2.2 Epidermis 3


1.2.3 Dermis 6


1.2.4 Hypodermis 7


1.2.5 Skin Appendages 8


1.3 Skin Biology 9


1.3.1 Homeostasis: Epidermal Self-renewal 9


1.3.2 Formation of aWater Barrier 10


1.3.3 Getting Across theWater Barrier 11


References 12


2 Wound Healing and Its Imaging 15
Jiah Shin Chin, Leigh Madden, Sing Yian Chew, Anthony R.J. Phillips and David L. Becker


2.1 Hemostasis and Essential Inflammation 15


2.2 Re-epithelialization 18


2.3 Granulation Tissue Formation 19


2.4 Scar Tissue Formation 20


2.5 Imaging of Wound Healing 21


2.6 Macroscopic Digital Imaging for Wound Size 22


2.7 Hyperspectral and Multispectral Imaging 22


2.8 Near-Infrared Spectroscopy 23


2.9 Raman Imaging 23


2.10 Confocal Microscopy 24


2.11 Multiphoton Imaging and Second Harmonics 24


References 27


3 Common Skin Diseases: Chronic Inflammatory and Autoimmune Disorders 35
Navin Kumar Verma, Maurice Adrianus Monique van Steensel, Praseetha Prasannan, Zhi Sheng Poh, Alan D. Irvine and Hazel H. Oon


3.1 Introduction 35


3.2 Psoriasis 36


3.2.1 Definition and Prevalence 36


3.2.2 Clinical Features, Pathogenesis, and Pathophysiology 37


3.2.3 Diagnosis 39


3.2.4 Therapy 40


3.3 Atopic Dermatitis (AD) 40


3.3.1 Definition and Prevalence 40


3.3.2 Clinical Features, Pathogenesis, and Pathophysiology 41


3.3.3 Diagnosis 42


3.3.4 Therapy 43


3.4 Scleroderma 43


3.4.1 Definition and Prevalence 43


3.4.2 Clinical Features, Pathogenesis, and Pathophysiology 44


3.4.3 Diagnosis 44


3.4.4 Therapy 45


3.5 Der