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Animal Models for Human Cancer

Discovery and Development of Novel Therapeutics

Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for cancer therapies, addressing the widely recognized lack of reliable and reproducible results. Les mer

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Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for cancer therapies, addressing the widely recognized lack of reliable and reproducible results.
Following a short historical introduction and a discussion of the ethics surrounding animal experiments, the book describes correct study design as well as the handling and housing of animals. It then goes on to describe the animal models available for different cancer types, from natural cancer models in mice and dogs to humanized animals. An evaluation of previously unpublished long-term data from the Swiss canine and feline cancer registry is also included. The final part of the book reviews the lessons learned over the last decade on how to interpret data from animal studies for improving human therapy and gives recommendations for future drug development.

Detaljer

Forlag
Wiley-VCH Verlag GmbH
Språk
Engelsk
ISBN
9783527695911
Utgivelsesår
2016
Format
Kopibeskyttet PDF (Må leses i Adobe Digital Editions)

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Yong-Su Zhen
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