Construction of Analogy–Based Research Progr – The Lock–and–Key Analogy in 20th Century Biochemistry
When the German chemist Emil Fischer presented his lock-and-key hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical structure and biological specificity. Les mer
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When the German chemist Emil Fischer presented his lock-and-key hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical structure and biological specificity. Rebecca Mertens explains the appeal of the lock-and-key analogy by its role in model building and in the construction of long-term, cross-generational research programs. She argues that a crucial feature of these research programs, namely ascertaining the continuity of core ideas and concepts, is provided by a certain way of analogy-based modelling.
Detaljer
- Forlag
- Transcript Verlag
- Innbinding
- Paperback
- Språk
- Engelsk
- ISBN
- 9783837644425
- Utgivelsesår
- 2021
- Format
- 23 x 15 cm