"This book is a fittingly titled, well-written publication. As a lengthy read, Stiehm's utility proves more to be as a comprehensive and informative reference book and guide for clinicians and any other readers interested in immunodeficiency. Readers will be able to easily navigate this well-organized text that provides outstanding details pertaining to immunodeficiencies and their common presentations, diagnostic approaches, and laboratory evaluations for diseases and a focused discussion on immunodeficiency management. Each chapter guides the reader by setting the tone with an overview or introduction, priming the reader for the in-depth text. Furthermore, the reader will find in-color illustrations, pictures, and imaging, which provides a visual aid in helping to solidify the understanding for the rare and complicated conditions discussed. In addition, of great value are the authors' use of tables that serve as an excellent quick reference for a plethora of topics ranging from various syndromes and their associated gene defects to therapeutic uses of vaccines in patients with immunodeficiency." --Annals of Allergy, Asthma and Imunology "With over 100 contributors, this current edition serves as a comprehensive resource on immunodeficiency disorders. It presents an up-to-date reference book with detailed information on all aspects of the subject. This authoritative collection is a reliable resource for practitioners, academicians, and researchers in the field." --Doody "Readers will indeed benefit from this fantastic reference book to help navigate the care of patients with rare conditions of inborn errors of immunity while understanding the genetic defects and pathophysiology of these conditions. Stiehm’s discussion of important clinical concepts bridges the gap between basic science immunology and how to apply it to the diagnosis and management of patients. The book is expertly written and will be an asset on the shelf of every immunologist." --Ann Allergy Asthma Immunol