This volume introduces the reader to the latest experimental and bioinformatics methods for DNA sequencing, RNA sequencing,
cell-free tumour DNA sequencing, single cell sequencing, single-cell proteomics and metabolomics. Chapters detail advanced
analysis methods, such as Genome-Wide Association Studies (GWAS), machine learning, reconstruction and analysis of gene regulatory
networks and differential coexpression network analysis, and gave a practical guide for how to choose and use the right algorithm
or software to handle specific high throughput data or multi-omics data. Written in the highly successful Methods in Molecular
Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents,
step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Computational Systems Biology: Methods and Protocols aims to ensure successful results in
the further study of this vital field.