Understanding the Gut Microbiota
This book discusses the community of microbial species (the microbiota, microbiome), which inhabits the large bowel of humans.
Written from the perspective of an academic who has been familiar with the topic for 40 years, it provides a long-term perspective of knowledge about this high profile and fast-moving topic. Les mer
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This book discusses the community of microbial species (the microbiota, microbiome), which inhabits the large bowel of humans.
Written from the perspective of an academic who has been familiar with the topic for 40 years, it provides a long-term perspective
of knowledge about this high profile and fast-moving topic. Building on general ecological principles, the book aims to help
the reader to understand how the microbiota is formed, how it works, and what the consequences are to humans. Understanding
the Gut Microbiota focuses on conceptual progress made from studies of the human bowel microbiota. Where appropriate, it draws
on knowledge obtained from other animal species to provide conceptual enlightenment, but this is essentially a book about
humans and their bowel microbes. Particular research approaches are recommended to fill knowledge gaps so that fundamental
ecological theory and information about the microbiota can be translated into benefits for human health. The relationship
between food for humans and resulting food for bowel bacteria emerges as an important topic for consideration.
This concise scholarly treatise of the microbiota of the human bowel will be of great interest and use as a text and reference work for professionals, teachers and students across a wide range of disciplines, including the health sciences, general biology, and food science and technology. The provision of handy explanation of terms means that those with a general interest in science can also read the book with enjoyment.
This concise scholarly treatise of the microbiota of the human bowel will be of great interest and use as a text and reference work for professionals, teachers and students across a wide range of disciplines, including the health sciences, general biology, and food science and technology. The provision of handy explanation of terms means that those with a general interest in science can also read the book with enjoyment.
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Utgitt:
2017
Forlag: John Wiley & Sons Inc
Innbinding: Innbundet
Språk: Engelsk
Sider: 184
ISBN: 9781118801420
Format: 24 x 18 cm
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Preface vii Acknowledgements ix 1 Introduction 1 References 4 2 Prime Facts 7 Summary 14 Explanation of
Terms 15 References 16 3 A Sense of Community 19 Summary 33 Explanation of Terms 33 References 35 4 Assembling
Communities 39 Summary 55 Explanation of Terms 55 References 56 5 Bowel Society 63 References 69 6 Chemostat
Bowel 71 Summary 82 Explanation of Terms 82 References 83 7 Revealing Secret Lives 87 Summary 98 Explanation
of terms 98 References 101 8 Remembrance of Microbes Past 105 Summary 111 References 112 9 Out of Tune: Dysbiosis
115 Summary 130 Explanation of Terms 130 References 132 10 We may be Lost, but we re Making Good Time 139
Particularly Important Considerations 143 Running Out of Fuel? 145 The End of the Journey 146 References 146 Addendum:
A Brief Summary of Technological Aspects of ]omics 149 General Features of Nucleic Acid-based Technology 149 Older
Electrophoretic Methods for Screening Microbiota Compositions 150 Fluorescent Probes (FISH/FC) 151 Measuring the Abundance
of Bacterial Groups by qPCR 152 Using DNA Chips to Screen Microbiota Compositions 153 Detailed Phylogenetic Analysis
154 Metagenomics: Determining the Functional Capacity of Microbiotas 155 Metatranscriptomics: Microbiota Biochemical
Pathways in Action 156 Metaproteomics 157 Metabolomics 157 Summary 158 References 159 Index 163
Professor Gerald W. Tannock is based at the University of Otago and was awarded a Professorial Chair in 1996. He was awarded
a Royal Society of New Zealand Silver Medal in 2000 for his contributions to science and technology and was elected a Fellow
of the American Academy of Microbiology in 2002.
Professor Tannock's research concerns the communities of bacteria that inhabit the gastrointestinal tract of animals. Research projects include the microbiology of inflammatory bowel diseases, the use of a unique colony of Lactobacillus-free mice in investigating the molecular foundations of gut autochthony using lactobacilli as model bacteria, engineering bowel communities by dietary manipulation, and the impact of bifidobacterial species on the activation of human dendritic cells with respect to atopic diseases. Professor Tannock's expertise has added an important microbiological facet to national and international, multi-disciplinary clinical studies in recent years.
Professor Tannock's research concerns the communities of bacteria that inhabit the gastrointestinal tract of animals. Research projects include the microbiology of inflammatory bowel diseases, the use of a unique colony of Lactobacillus-free mice in investigating the molecular foundations of gut autochthony using lactobacilli as model bacteria, engineering bowel communities by dietary manipulation, and the impact of bifidobacterial species on the activation of human dendritic cells with respect to atopic diseases. Professor Tannock's expertise has added an important microbiological facet to national and international, multi-disciplinary clinical studies in recent years.