New Technologies and Perinatal Medicine

Prediction and Prevention of Pregnancy Complications

Moshe Hod (Redaktør) ; Vincenzo Berghella (Redaktør) ; Mary D'Alton (Redaktør) ; Gian Carlo Di Renzo (Redaktør) ; Eduard Gratacos (Redaktør) ; Vassilios Fanos (Redaktør)

The potential impact of work being conducted in genomics, proteomics, and metabolomics upon clinical practice for gynecologists is immense but not yet completely appreciated. This groundbreaking text from international experts examines the newest topics on the perinatal agenda and gives clinicians a real look into the future via the newest methodologies. Les mer
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Leveringstid: Sendes innen 7 virkedager

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The potential impact of work being conducted in genomics, proteomics, and metabolomics upon clinical practice for gynecologists is immense but not yet completely appreciated. This groundbreaking text from international experts examines the newest topics on the perinatal agenda and gives clinicians a real look into the future via the newest methodologies.

Fakta

Innholdsfortegnelse

List of contributors





Preface


Introduction: Why do we need Omics and Systems Biology
Joe Leigh Simpson and Moshe Hod





A Pregnancy Complications: Setting the Scene


1. The Mother: Adaptation to Pregnancy and normal metabolism


Irene Cetin, Francesca Parisi, Alice Zavatta, and Roberta Milazzo


2. Maternal and fetal normal and abnormal nutrition


Sarah Louise Killeen, Eilleen C O'Brien, and Fionnuala M McAuliffe


3. The Great Obstetrical Syndromes: It's all in the placenta
Martin Gauster and Gernot Desoye


4. Embryo-specific communication and interaction with the maternal environment: The role of PreImplantation Factor
Eytan R Barnea and Michael Stark


5. Normal and abnormal fetal growth


Javier Caradeux, Eduard Gratacos, and Francesc Figueras


6. Pre-term labor and birth


Vincenzo Berghella and Eduardo da Fonseca


7. Gestational Diabetes Mellitus
Silvia Vannuccini and Federico Mecacci


8. Pre-eclampsia


Jon Hyett and Liona Poon


9. Maternal obesity


Tahir A. Mahmood and Rohan Chodankar


10. Maternal health: Immediate, short-, and long-term complications following pregnancy


Gil Gutvirtz, Omri Zamstein, and Eyal Sheiner


11. The fetus and the neonate: Immediate, short, and long term impact
Umberto Simeoni and Elie Saliba


12. The cost of pregnancy complications related to non-communicable diseases and the cost effectiveness of interventions to address them


Anil Kapur, Jon Hyett, and H David McIntyre





B Towards Prediction and Prevention


13. Integrated System Biology approaches to Fetal Medicine problems


Jezid Miranda, Fatima Crispi, and Eduard Gratacos


14. Omics and female reproduction


Galia Oron


15. The maternal genome and pregnancy outcomes
Nagendra K. Monangi, Ge Zhang, Mikko Hallman, Kari Teramo, Bo Jacobsson, and Louis J Muglia


16. Placental development and Omics


Sylvie Hauguel-de Mouzon, Gernot Desoye, and Silvija Cvitic


17. Placental metabolomics in obese pregnancies
Irene Cetin, Chiara Novielli, and Chiara Mando


18. The methylome and epigenetics markers


Skevi Kyriakou, Marios Ioannides, George Koumbaris, and Philippos Patsalis


19. The microbiome and pregnancy complications
Maria Carmen Collado and Omry Koren


20. Small non-coding RNAs as biomarkers for pregnancy complications
Liron Yoffe, Meitar Grad, Avital Polsky, Moshe Hod, and Noam Shomron


21. Urine metabolomics and proteomics in prenatal health


Daniela Duarte, Maria do Ceu Almeida, Pedro Domingues, and Ana M. Gil


22. The metabolomics and perinatal complications


Flaminia Bardanzellu, Moshe Hod, and Vassilios Fanos


23. Metabolomics in normal and pathologic pregnancies


Antonio Ragusa, Alessandro Svelato, and Sara D'Avino


24. Metabolomics in amniotic fluid


Alexandra-Maria Michaelidou, Foteini Tsakoumaki, Maria Fotiou, Charikleia Kyrkou, and Apostolos P. Athanasiadis


25. Omics and coagulation disorders in pregnancy


Sara Ornaghi and Michael J Paidas


26. The omics and preeclampsia
Piya Chaemsaithong and Liona C. Poon


27. Single Nucleotide Polymorphisms and pregnancy complications


Federica Tarquini, Giuliana Coata, Elena Picchiassi, and GianCarlo Di Renzo
28. Metabolomics and perinatal cardiology


Roberta Pintus, Angelica Dessi, and Vassilios Fanos


29. Metabolomics and human breast milk: a unique and inimitable food for infants


Flamina Cesare Marincola, Sara Corbu, Roberta Pintus, Angelica Dessi, and Vassilios Fanos


30. Neurodevelopment and placental omics
Despina D. Briana and Ariadne Malamitsi-Puchner


31. Early life complications, placental genomics, and the risk for neurodevelopmental disorders in