Clinical Neurovirology

Avindra Nath (Redaktør) ; Joseph R. Berger (Redaktør)

This is a comprehensive reference that includes the basic science, clinical features, imaging, pathology and treatment of specific viral entities affecting the central nervous system (CNS). It will assist professionals in their attempt to identify, examine and manage viral CNS infections and unravel the therapeutic and diagnostic challenges associated with viral CNS disorders. Les mer
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Innbundet
Innbundet
Vår pris: 2531,-

(Innbundet) Fri frakt!
Leveringstid: Ikke i salg
På grunn av Brexit-tilpasninger og tiltak for å begrense covid-19 kan det dessverre oppstå forsinket levering.

Om boka

This is a comprehensive reference that includes the basic science, clinical features, imaging, pathology and treatment of specific viral entities affecting the central nervous system (CNS). It will assist professionals in their attempt to identify, examine and manage viral CNS infections and unravel the therapeutic and diagnostic challenges associated with viral CNS disorders.


Key Features








Features MRI scans, histopathology and lined diagrams showing pathophysiology







Much has happened in our understanding of CNS infections in recent years and a comprehensive book that covers the entire subject is much needed.







There is ongoing interest in infectious disease. The increasing globalization of medicine is putting demands on many more people to become familiar with issues from around that world that they did not see in training.

Fakta

Innholdsfortegnelse

Preface


Acknowledgments


Editors


Contributors


PART I. INTRODUCTION: EPIDEMIOLOGY, SOCIOECONOMIC IMPACT, AND CHALLENGES AHEAD


1. Introduction to virus structure, classification, replication, and hosts


Philippe Simon and Kevin M. Coombs


2. Neuropathogenesis of viral infections


Avindra Nath and Joseph R. Berger


3. An approach to pathogen discovery for viral infections of the nervous system


Prashanth S. Ramachandran and Michael R. Wilson


4. Neuropathology of CNS viral infections and the role of brain biopsy in the diagnosis


Susan Morgello


PART II. DNA VIRUSES


5. Herpes simplex viruses


Israel Steiner and Felix Benninger


6. Varicella zoster virus infection


Don Gilden, Randall J. Cohrs, Dallas Jones, and Maria A. Nagel


7. Epstein-Barr virus and the nervous system


Alexandros C. Tselis, Kumar Rajamani, and Pratik Bhattacharya


8. Cytomegalovirus


Joseph R. Berger


9. Progressive multifocal leukoencephalopathy


Eric M. L. Williamson and Joseph R. Berger


10. Adenovirus


Jennifer McGuire and Joseph R. Berger


PART III. RETROVIRUSES


11. HIV neurological complications


Alessandro Fois and Bruce Brew


12. Human T lymphotropic virus type 1 (HTLV-1)


Shila Azodi and Steven Jacobson


PART IV. RNA VIRUSES


13. Rabies and other lyssaviruses


Thiravat Hemachudha, Jiraporn Laothamatas, and Henry Wilde


14. Neurological manifestations of West Nile virus


Daniel E. Smith, J. David Beckham, Daniel M. Pastula, and Kenneth L. Tyler


15. Chikungunya virus and Japanese encephalitis virus


Jennifer L. Lyons


16. Arthropod-borne virus encephalitis


Joseph R. Berger


17. Enteroviruses


Karen Straube-West and Burk Jubelt


18. Measles and its neurological complications


Benedikt Weissbrich and Jurgen Schneider-Schaulies


19. Rubella


Avindra Nath


20. Influenza neurologic complications


Larry E. Davis and Jennifer R. Plourde


21. Nipah encephalitis, a fatal encephalitis with bats as reservoir


Chong-Tin Tan and Kum-Thong Wong


PART 5. MISCELLANEOUS


22. Von Economo's encephalitis


Joseph R. Berger


23. Neurological events following immunizations


James J. Sejvar


24. Central nervous system viral infections complicating immunosuppression


Amy A. Pruitt


25. Post-viral syndromes


Anusha K. Yeshokumar, Eliza Gordon-Lipkin, and Brenda Banwell


26. Viral neuro-oncogenesis: Polyomaviruses and brain tumors


Martyn K. White, Sidney E. Croul, and Kamel Khalili


27. Autoimmune disorders that can be mistaken for viral illness


Maxwell Greene and Eric Lancaster


28. Antiviral therapeutics for viral infections of the central nervous system


Richard Whitley


29. Neurological manifestations of coronavirus infections


Avindra Nath and Joseph R. Berger


Index

Om forfatteren

Avindra Nath





Dr. Nath is the Chief of the Section of Infections of the Nervous System at the National Institute of Neurological Disorders and Stroke. He was previously Professor in the Department of Neurology and Director of the Division of Neuroimmunology and Neurological Infections at Johns Hopkins University. His career has been dedicated to studying the clinical manifestations, pathophysiology and developing treatment for brain infections since the beginning of the AIDS pandemic. He has traveled to several countries to study these infections including Liberia during the Ebola epidemic. He teaches medical students, residents and clinical fellows on CNS infections for which he has received several teaching awards. He frequently talks at grand rounds, seminars and conferences around the world on viral infections of the brain and has been teaching courses on viral encephalitis at the American Academy of Neurology for over 20 years. His laboratory research is focused mainly on retroviral infections particularly HIV infection. More recently, his laboratory is studying the pathophysiology of Ebola and Zika viruses. He is the past President of the International Society of Neurovirology (ISNV) and an elected member of the Association of American Physicians. He is the recipient of the Pioneer award from the ISNV and the Wybran award from the Society of Neuroimmune Pharmacology.





Joseph R. Berger


Dr. Berger, M.D., is Professor of Neurology and Associate Chief of the Multiple Sclerosis Division of the Department of Neurology at the Perelman School of Medicine at the University of Pennsylvania in Philadelphia. His career has been dedicated to the diagnosis, treatment and investigation of neuroinfectious and neuroinflammatory disorders. His foray into neuroinfectious diseases started with the investigation of the neurological complications of HIV/AIDS while at the University of Miami at the inception of the AIDS pandemic and an endowment there established the Whigham-Berger Endowed Chair, the first endowed chair for the study of the neurological complications of HIV/AIDS. Dr. Berger continued his research in HIV and PML while at the University of Kentucky where he was Chairman of the Department of Neurology from 1995 to 2013. With Dr. Robert Levy, he co-founded and co-chaired the international Neuroscience of HIV conference. He is a fellow of the American College of Physicians, American Academy of Neurology and the American Neurological Association. Among his many awards are the Pioneer Award from the International Society of Neurovirology and the Distinguished Teaching Award from the American Neurological Association.